Enjoy fast, free delivery, exclusive deals, and award-winning movies & TV shows with Prime
Try Prime
and start saving today with fast, free delivery
Amazon Prime includes:
Fast, FREE Delivery is available to Prime members. To join, select "Try Amazon Prime and start saving today with Fast, FREE Delivery" below the Add to Cart button.
Amazon Prime members enjoy:- Cardmembers earn 5% Back at Amazon.com with a Prime Credit Card.
- Unlimited Free Two-Day Delivery
- Streaming of thousands of movies and TV shows with limited ads on Prime Video.
- A Kindle book to borrow for free each month - with no due dates
- Listen to over 2 million songs and hundreds of playlists
- Unlimited photo storage with anywhere access
Important: Your credit card will NOT be charged when you start your free trial or if you cancel during the trial period. If you're happy with Amazon Prime, do nothing. At the end of the free trial, your membership will automatically upgrade to a monthly membership.
-5% $38.13$38.13
Ships from: Amazon.com Sold by: Amazon.com
$25.27$25.27
Ships from: Amazon Sold by: angelscorner
Download the free Kindle app and start reading Kindle books instantly on your smartphone, tablet, or computer - no Kindle device required.
Read instantly on your browser with Kindle for Web.
Using your mobile phone camera - scan the code below and download the Kindle app.
First in Fly: Drosophila Research and Biological Discovery Hardcover – March 9, 2018
Purchase options and add-ons
A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny?
Drosophila’s importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases.
Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these “first in fly” findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.
- Print length272 pages
- LanguageEnglish
- PublisherHarvard University Press
- Publication dateMarch 9, 2018
- Dimensions6.5 x 1 x 9.5 inches
- ISBN-100674971019
- ISBN-13978-0674971011
Frequently bought together
Customers who bought this item also bought
Editorial Reviews
Review
“Mohr reveals a raft of breakthroughs discovered ‘first in fly,’ such as the molecular mechanisms of circadian rhythm. Serious science, elegantly described.”―Barbara Kiser, Nature
“Mohr’s First in Fly: Drosophila Research and Biological Discovery takes you into the labs to examine one small organism that makes so much biomedical and genetic research possible…Its deep dive into the incredible and outsized role these tiny flies play in scientific research will not disappoint.”―Mary Beth Griggs, Popular Science
“Introduces a variety of fundamental biological concepts discovered over the last century, thanks to fruit flies…This fascinating book will especially appeal to students of the life sciences and the history of science, and to all curious people.”―Forbes
“The book is an inspiring read that improves from chapter to chapter. It is loaded with relevant, thought-provoking and well-researched information, clearly illustrating the important role of past and present fly research and providing a vision for the future. For its original approach, it deserves a place on the bookshelves not only of fly researchers but of all who care about responsible biomedical research.”―Andreas Prokop, Times Higher Education
“Stephanie Mohr brilliantly illuminates the discovery and relevance of the fruit fly. She transforms vague public awareness of Drosophila into a breathtaking landscape of research, building a case for pure science as the source of most scientific surprises, revolutions, and ultimately, practical applications. Really, everything has been touched by flies; from the international laws impacted by mustard gas and radiation mutations to the testing of new drugs to the appreciation of how single egg cells turn into wonderfully complex bodies. This book illustrates why we should all be very grateful to these flies and the ‘fly people’ who study them.”―George Church, Harvard University
“First in Fly provides a superb foundation on which to explore new avenues in biology. Mohr presents a riveting account of discoveries made possible by research on the fruit fly, Drosophila melanogaster, over the past 110 years. No model organism has contributed more to our understanding of genetics and developmental biology. This book is highly recommended for scientists both young and established, and for all who wish to learn more about the origins of many commonly accepted facts in biology.”―Hugo Bellen, Baylor College of Medicine
“From the nature of genes to the secrets of behavior to cancer therapy, Mohr captures how fundamental research on the unassuming and ubiquitous fruit fly has driven revolutions in biology and medicine. The material is rich; the subject is timely; and the premise is powerful. An important read.”―David Bilder, University of California, Berkeley
“First in Fly is a reader-friendly yet scholarly account of fruit fly biology and genetics. As Mohr clearly presents, the fly provides the best system for understanding the basic mechanisms of development and disease, and how those mechanisms apply to all other animals, including humans.”―Peter Lawrence, University of Cambridge
“First in Fly distills a century of biology research on Drosophila into a set of exciting, mind-bending stories. Mohr captures the thrill of scientific discovery and the creative spirit of this research community, while clearly explaining the scientific findings and relating them to human biology and health. Her book tells a vital story about the remarkable extent of evolutionary conservation, and is both important in scope and a pleasure to read.”―Andrea Page-McCaw, Vanderbilt University
“An accessible resource for experts and non-experts alike, First in Fly beautifully articulates how the fruit fly has made enormous contributions to our understanding of genetics and biology. Stephanie Mohr demystifies the fruit fly through humor and facts, while also shedding light on how the study of one small and unquestionably valuable insect has contributed to the understanding of cognitive and biological processes.”―Giovanni Bosco, Dartmouth College
“A passionate, information-packed ode to Drosophila melanogaster and the ‘fly people’ who study it…We learn how discoveries first made in Drosophila contributed to breakthroughs in developmental genetics and signal transduction, and even help to advance space travel and cancer research today…Perhaps most importantly, this book talks openly and honestly about the processes of scientific research and discovery.”―Alice Laciny, History and Philosophy of the Life Sciences
About the Author
Product details
- Publisher : Harvard University Press (March 9, 2018)
- Language : English
- Hardcover : 272 pages
- ISBN-10 : 0674971019
- ISBN-13 : 978-0674971011
- Item Weight : 1.1 pounds
- Dimensions : 6.5 x 1 x 9.5 inches
- Best Sellers Rank: #967,518 in Books (See Top 100 in Books)
- #366 in Entomology (Books)
- #415 in Scientific Research
- #734 in Genetics (Books)
- Customer Reviews:
Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on Amazon-
Top reviews