Probolinggo is an area East Java which has beautiful tourism area, especially Gili Ketapang Island. This research purposes to know how the management system in Gili Ketapang Village Asset, Sumber Asih , Probolinggo Regency. The tourist attraction management system is an important indicator in determining the success of a tourist attraction, therefore the attraction of Gili Ketapang requires a good management system in order to become a leading attraction. Data collection techniques conducted in this study are observation techniques, unstructured interview techniques and documentary techniques. Determination technique of informant by using purposive sampling technique. Data analysis technique used is qualitative data. The conclusion of the discussion is the management system of Gili Ketapang tourist attraction on planning, organizing, actuating, and controlling, in each of the five components there are variables of tourism attraction, management and improvement of human resources, to...

Advanced stage follicular lymphoma (FL) is incurable by conventional therapies. In the present pilot clinical trial, we explored the efficacy and immunogenicity of a novel in situ immunotherapeutic strategy. Fourteen patients with untreated or relapsed stage III/IV FL were included and received local radiotherapy to solitary lymphoma nodes and intranodal injections of low-dose rituximab (5 mg), immature autologous dendritic cells, and granulocyte-macrophage colony-stimulating factor at the same site. The treatment was repeated 3 times targeting different lymphoma nodes. Primary end points were clinical responses and induction of systemic immunity. Five out of 14 patients (36%) displayed objective clinical responses, including 1 patient with cutaneous FL who showed regression of skin lesions. Two of the patients had durable complete remissions. Notably, the magnitude of vaccination-induced systemic CD8 T-cell-mediated responses correlated closely with reduction in total tumor area (r...

Objectifs En complement des parametres chiffres de condition physique que nous obtenons de facon systematique par l’evaluation a l’effort, nous avons mis en place une quantification de l’etat emotionnel du patient par un questionnaire de qualite de vie. Les resultats ont ete compares entre le debut et la fin du programme de readaptation cardiaque pour chaque patient. Methodes Le questionnaire est remis au patient en salle d’attente du test d’effort avec pour instruction « remplissez sans trop reflechir… » Le patient evalue ses sentiments a l’aide d’une echelle de 0 a 4, sur laquelle 65 sentiments sont regroupes en 7 emotions presentees sous forme d’une courbe. Resultats Quatre cent questionnaires ont etes remplis, saisis et compares. 164 hommes et 36 femmes, 59,7 ± 11,9 ans, 106 coronariens et 94 non coronariens, 83 patients operes et 117 non operes. Duree de sejour 24,4 ± 10,8 jours Ont ete diminuees et de facon significative : l’anxiete de 9,3 ± 5,1 a 6,6 ± 4,2 (p Conclusions Le ...

Cilj je radu bio napraviti pregled istraživanja o ozljedama mekih tkiva u vaterpolu, usporediti metodologije i dobivene rezultate, sjediniti rezultate uspostavom kriterija koji to dopuštanju te istaknuti i sistematizirati dobivene rezultate Generalni limiti svih uključenih studija, uključivo i njihov malen broj, jest mali broj ispitanika (od 5 do 31) na kojima su provedene. Nedostajale su kontrolne skupine ili međusubjektna kontrola. Uzorak je bio uglavnom ograničen na vrhunske športaše i nereprezentativan u smislu mogućih generalizacija. U većini istraživanja bol nije operacionalno definiran. Karakteristike mjernih instrumenata nisu uvijek bile procijenjene. Statističke analize nisu uvijek bile primjerene dizajnu studija. Mnogi zaključci doneseni su sukladno biomehaničkim mogućim i vjerojatnim razlozima nastanka patologija, ali ne i na ispitivanju pokreta. Buduće smjernice istraživanja moraju se odnositi na izbor i validiranje mjernih instrumenata i postupaka u dijagnostici športsk...

Mating system, sexual dimorphism, and the opportunity for sexual selection in